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Instruments & Equipment
LA635 - Large-Scale Cell Culture Observation Microscope
LA635 - Large-Scale Cell Culture Observation MicroscopeNew International Standard Infinity Optical System: 60mm parfocal distance, delivering higher resolution and longer objective working distance.Stable Frame Design: Weighs ≥36 kg; body features splash-resistant construction.Focusing System: Vertical travel range: 8mm upward, 3mm downward. Fine adjustment: 0.1mm per rotation; coarse adjustment: 5mm per rotation. Adjustable torque with user-definable upper focus limit.Objective Turret: ≥5-position objective turret, includes protective cover.Observation Modes: Brightfield and fluorescence systems available (two models to choose from).LED Illumination: Exceptionally long service life of ≥60,000 hours. Built-in fly-eye lens ensures uniformly bright illumination across the field of view at all magnifications.Condenser: Long working distance condenser with N.A. ≥0.30; adjustable working distance from 75mm to 720mm; includes universal phase contrast module.Large Combined Mechanical Stage: Features pulley design, providing stable support for large samples like cell factories and enabling smooth field of view adjustment. ItemDescriptionStandard ConfigurationMain Unitncludes body with transmitted light illumination column, 60,000-hour long-life LED light source, fly-eye illumination lens assembly, and 5-hole objective turret.Eyepieces10X eyepieces, FOV 22, with independently adjustable diopters on both eyepieces.Primary Observation Objectives4X,10X,20X,40Xapodized phase contrast objectives, reduce haloing at cell and nuclear edges.Secondary Observation Objectives4X plan achromatic objective.StageLarge sliding stage, enables observation of the entire cell factory plane.CondenserElectrically powered Lifting condenser, allows for stepless vertical height adjustment.Power Supply220VWeight36kgOptional AccessoriesCameraColor, 20 Megapixel, resolution 5440x3648ComputerIntel i5 processor, 8GB RAM, 1TB HDD, USB 3.0 interfaces.Validation3Q Validation Service
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Cell Dry Thawer
Cell Dry ThawerPrecision Dry-Block Cell Recovery System The Bocheng Cell Dry Thawer employs proprietary dry-block temperature control combined with integrated infrared thermographic monitoring to deliver rapid, waterless cell recovery. An AI-driven thermal algorithm optimizes the thaw curve in real time, achieving superior post-thaw viability compared with conventional water-bath methods. The system supports cell therapy manufacturing, stem cell research, biobanking, and clinical bedside use. Six Key Features▸ Infrared Thermographic MonitoringBuilt-in thermal imaging sensor continuously maps the temperature distribution across all sample positions, detecting partial thaw states and preventing localized overheating.▸ Waterless Dry-Block TechnologyMetal conduction blocks eliminate water-bath contamination risks entirely. No liquid media required — simplified cleaning and zero cross-contamination.▸ AI Adaptive Temperature ControlDeep-learning thermal model auto-generates an optimized ramp profile based on sample volume and initial temperature, ensuring recovery within the ideal thaw window.▸ Full Data TraceabilityTemperature, time, and operator data are logged continuously and exported via USB or network — compliant with GMP, FDA 21 CFR Part 11, and ICH Q10.▸ Touchless Safe OperationFully enclosed chamber design prevents direct contact with cryogenic samples or heated blocks, protecting both personnel and cell viability.▸ Intuitive 7-inch TouchscreenHigh-resolution colour display shows live thaw curves and thermal maps. Multi-language UI; programmable protocols stored per sample type. Standard Thawing Workflow01 Step 1 — Retrieve SampleRemove the cryovial or bag from liquid nitrogen or −80 °C storage. Verify label identity.02 Step 2 — Load SampleInsert the cryovial into the designated port. Confirm seating and block contact.03 Step 3 — Select ProtocolChoose the sample type and thaw program on the touchscreen. Confirm start temperature.04 Step 4 — Initiate ThawPress Start. The AI controller executes the optimized ramp profile automatically.05 Step 5 — Transfer CellsAudible alert signals completion. Immediately transfer cells to medium for downstream use. Post-Thaw Viability ComparisonBocheng Dry Thawer99.91%Mean Post-Thaw Viabilityn=50, CD34⁺ HSCsConventional Water Bath99.83%Mean Post-Thaw ViabilityMatched sample cohortData source: Bocheng Internal Validation Report, 2025. Viability measured by trypan blue exclusion. Sample: CD34⁺ haematopoietic stem cells. Product SpecificationsFour model variants are available to accommodate different throughput requirements, from single-bench research laboratories to high-volume GMP cell therapy facilities. ParameterBC-DT02 (2-Port)BC-DT04 (4-Port)BC-DT06 (6-Port)BC-DTB (Bag Type)Compatible Container2 mL cryovials2 mL cryovials2 mL cryovialsCryo bags 50–250 mLThroughput (per run)2461 bagTemperature Range−10 to +45 °C−10 to +45 °C−10 to +45 °C−10 to +40 °CTemperature Accuracy±0.1 °C±0.1 °C±0.1 °C±0.2 °CHeating Rate1–20 °C/min adjustable1–20 °C/min adjustable1–20 °C/min adjustable1–15 °C/min adjustableThermal Imaging Res.160 × 120 px160 × 120 px160 × 120 px320 × 240 pxDisplay7" colour touch7" colour touch7" colour touch10" colour touchData InterfaceUSB / RS-232USB / RS-232USB / RS-232 / NetworkUSB / NetworkPower SupplyAC 100–240 V 50/60 HzAC 100–240 V 50/60 HzAC 100–240 V 50/60 HzAC 100–240 V 50/60 HzRated Power120 W180 W240 W300 WDimensions (mm)200×160×140280×180×140350×180×140400×280×180Weightapprox. 3.5 kgapprox. 4.8 kgapprox. 6.2 kgapprox. 8.5 kgCertificationsCE / ISO 13485CE / ISO 13485CE / ISO 13485CE / ISO 13485 Model Selection GuideBC-DT02 (2-Port) — Ideal for low-throughput research labs and clinical bedside recovery.BC-DT04 (4-Port) — Suited to mid-volume cell laboratories and clinical collection centres.BC-DT06 (6-Port) — Designed for high-throughput GMP cell manufacturing suites.BC-DTB (Bag Type) — Purpose-built for large-volume cryobags in CAR-T and large-scale cell therapy workflows; features enhanced thermal resolution. Application Areas▸ Cell TherapySupports standardised recovery of CAR-T, NK, and TCR-T cell products under GMP-compliant conditions. Compatible with regulatory audit documentation workflows.▸ Stem Cell ResearchValidated for haematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs), and induced pluripotent stem cells (iPSCs).▸ BiobankingEnables reproducible batch recovery across large-scale sample repositories. Full traceability ensures consistent sample quality.▸ Reproductive MedicineApplicable to cryopreserved sperm, oocytes, and embryo recovery with high precision and continuous process monitoring.▸ Drug Discovery & ToxicologySupports rapid, standardised recovery of cell lines such as CHO and HEK293, improving assay reproducibility and screening throughput.▸ Clinical InfusionCompact footprint enables deployment in infusion suites for immediate post-thaw administration, minimising ex vivo time. Service & Technical SupportInstall
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Plate Washer
Product OverviewThe Bio-Chem Plate Washer employs non-contact centrifugal technology to efficiently remove liquid from 96-well, 384-well, and 1536-well microplates without the need for disposable tips. This environmentally friendly technology enables contamination-free operation for cell-based assays, bead-based assays, genomics experiments, and ELISA assays — with zero residual liquid, thereby completely eliminating background interference and result variability in detection data. The integrated dispensing module further dramatically enhances the overall operational efficiency of assay workflows.Product Features1. Centrifugal MethodThe Bio-Chem Plate Washer uses centrifugal technology rather than aspiration to clear liquid from microplates. Through its centrifugation mechanism, the microplate rotates around a horizontal axis, and liquid is expelled from the wells under centrifugal force, immediately exiting the rotor chamber via a passive drainage system. Centrifugal liquid removal significantly reduces residual volume and variability during media exchange or supernatant removal. Lower background noise and variability translate to higher-quality, more reproducible data for cell screening. In magnetic bead-based assays, the Bio-Chem Plate Washer eliminates the need for disposable tips, minimizes bead loss, and dramatically shortens operating cycles.2. Liquid InputIn standard configuration, up to seven input ports can deliver liquids to a shared dispensing head and internal fluid channels. Each liquid input port is independently addressable and can be calibrated via the Bio-Chem Plate Washer's built-in software.3. Multi-Plate Adapter CompatibilityAngled or straight dispensing heads are available for 6-well, 12-well, 24-well, 48-well, 96-well, 384-well, and 1536-well plates. The Bio-Chem Plate Washer's graphical user interface supports selection of cell-friendly dispensing modes, minimizing the loss of weakly adherent or suspension cells.4. Linear Drive SystemThe Bio-Chem Plate Washer's linear drive technology positions plates with micrometer-level precision during the dispensing process, ensuring that dispensing nozzles accurately reach the target wells for each application. For example, dispensing nozzles can be directed toward the leading edge of the well wall, thereby preventing detachment of sensitive cells. Technical Specification ParameterSpecificationApplication ScenariosNon-contact media exchange and liquid removal with near-zero, reproducible residual volume Magnetic carrier support for 96/384/1536-well plate bead washingCompatibilitySupports all SBS-standard microplates (up to 17.4 mm height), including 1536-well strip plates / slides Custom format programming supported; can dispense to 96/384-well plates Optional 1536-well plate dispensing capabilityCentrifuge SystemComputer-controlled high-power servo motor driving a symmetrical rotor Plates positioned horizontally, opening facing outward for liquid expulsionResidual Volume0.01 µL to 5 µL/well (method-dependent)Centrifuge ParametersSpeed range: 3 – 3,500 RPM (corresponding to 630 g centrifugal force) Acceleration: <1,500 RPM/s Deceleration: <1,000 RPM/s Maximum dry-weight imbalance: 15 g at 3,500 RPM / 20 g at 2,000 RPM / 35 g at 1,500 RPM / 70 g at 1,000 RPMDispensing ParametersNozzle type: angled / straight, adjustable Dispensing pressure: 5 levels adjustable (~25%–100%) Dispensing speed: 96-well plate: 100 µL / 7 s 384-well plate: 50 µL / 13 s 1536-well plate: 8 µL / 13 s Precision: 96/384-well: >1 µL @ 100 µL, CV <3% 1536-well: >3 µL @ 10 µL, CV <5%Internal Dead Volume8 mL (from inlet fitting to nozzle tip)Software & OperationPC-based graphical interface with preloaded application method library Supports custom method editing and workflow programmingSafety ProtectionAutomatic shutdown protection upon excessive vibration Sensor-controlled interlock doorDimensions (L × W × H)352 mm × 700 mm × 206 mm (without screen); 366 mm height with screenWeight31.5 kgPower Requirements220 V, 550 WAmbient Temperature15 °C – 55 °C (60 °F – 130 °F)
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Automatic Plate Sealer
Product Introduction:Our fully automatic plate sealer adopts a roller pressure design, providing tight sealing without liquid leakage, effectively preventing sample loss and cross-contamination. It is mainlyused for PCR plate sealing. The instrument is simple to operate, with flexible software parameter settings and fast, easy sealing process, greatly improving work efficiency.Product Features:The sealing process is fast and efficient, with a sealing cycle as short as 15 seconds, and single-step sealing can be completed in as fast as 3 seconds. Consumable replacement is convenient - after heat sealing, the plate sealing film is cut and leaves a small edge, making bottom film recycling very convenient.Can be used as a standalone unit or integrated into other automated workstation platforms;Interfaces: Supports USB, RS232, RS485 interfaces, and can also be controlled via TTL signals.One-button sealing, compatible with various PCR 96-well plates;Adapters are convenient to replace and can also be customized according to experimental requirements;Tight sealing: Adheres to the plate through dual action of pressure and heating, providing high sealing degree; No evaporation: Meets the need for preventing evaporation in gene amplification experiments; Excellent consistency and repeatability: The equipment supports flexible sealing time settings from 1 to 10 seconds, temperature control accuracy up to ±1°C, and automatically recognizes sealing height, ensuring stable and uniform sealing results.Technical Parameters:Product NameFully Automatic Plate SealerModelBC001Sealing MethodPressure SealingCompatible Film TypeRoll Pressure-Sensitive FilmCompatible Film ModelBC-RTQ-RLCompatible Film Specification150 sheets/rollCompatible Consumable Type96-well PCR plate (no skirt, semi-skirt, full skirt)Operation InterfaceButton operation or external LCD touchscreenSealing Time8 secondsSignal InterfaceCompatible with USB or RS232, RS485 interfaces, also controllable via TTL signalsRated Power200WProduct Dimensions240×405×412mm(L×W×H)Net Weight18.5kg Operating Steps:Starting the Equipment:According to the instructions in the equipment operation manual, correctly connect the equipment power supply.Turn on the equipment power switch and wait for the equipment self-check to complete.The emergency stop button popping up is the initial state. For first-time startup, press the reset button once - the plate feeding fixture will automatically return to the initial position, and the film feeding axis will rotate for one film length. Please remove the peeled film at this time to prevent it from being drawn into the pressure roller. After the above two actions stop, you can place the multi-well plate and press the start button - the multi-well plate will be automatically sealed and return to the initial position. Without pressing the emergency stop, there is no need to press the reset button again. After loading, directly press the start button, and the equipment will automatically complete the sealing action and return to the initial position.Parameter Settings:According to actual needs, set equipment parameters through the operation panel or software interface (for models with HMI screen).After confirming the parameter settings are correct, save and apply.Starting Operation:According to the instructions in the equipment operation manual, start the equipment to begin work.During operation, observe the equipment running status and indicator light changes.Film Count Writing:For models without HMI screen, film count writing method: 1. Press the emergency stop button; 2. Press the reset button and start button simultaneously and hold for more than 2 seconds, the parameter will automatically write 150 sheets per roll.Release the buttons, turn the emergency stop button to pop up, then press the reset button once. All equipment components will automatically find the home position. Note: When the film axis resets, please manually remove the peeled film.All components return to initial position, ready to start sealing.Monitoring and Adjustment:During equipment operation, regularly monitor equipment status and output results.If parameter adjustment is needed, please operate according to the equipment operation manual.If film jam or equipment abnormality occurs during operation, please press the emergency stop button directly, and the equipment will stop running immediately.Ending Operation:After the equipment completes its work task, shut down the equipment according to the instructions in the equipment operation manual.Disconnect the equipment power supply and clean the surrounding environment of the equipment.PrecautionsSafety Operation: When operating the equipment, please strictly follow the safety regulations in the equipment operation manual. During equipment operation, do not put your hands or foreign objects into the rotating shaft to avoid crushing injuries, equipment damage, or other accidents.Maintenance: Perform regular maintenance on the
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Continuous Flow Cell Concentrator
Continuous Flow Cell ConcentratorThe Ideal Choice for Personalized MedicineShanghai Biochem Biotech Co., Ltd.1. Product OverviewDesigned for harvesting CHO cells, stem cells, and other cell types, this system is widely used in the biotechnology and pharmaceutical industries. It is capable of collecting stem cells, CHO cells, immune cells, and other particles for biotech and pharmaceutical applications. Suitable for a broad range of users in cell therapy, antibody production, vaccine development, gene therapy, and mRNA research, including major pharmaceutical companies and biotech research institutions. User-friendly by design, it can be operated on a laboratory benchtop, within a cleanroom, or under a laminar flow hood.System FeaturesFully Closed SystemNo CIP or SIP RequiredHigh Cell Recovery RateLightweight Single-Use Module with Tubing AssemblyMaximum Relative Centrifugal Force of 6,600 × gContinuous Clarified Liquid Discharge & Intermittent Cell DischargeLow-Shear Separation ProcessRapid Single-Use Module Change-Out in Under 15 MinutesIntegrated Cooling System for High Cell Viability Post-HarvestFlow Rate Range: 10 to 1,200 mL/minThe separation system utilizes a gamma-irradiated, sterile single-use centrifugal module, eliminating the need for Clean-in-Place (CIP) or Sterilize-in-Place (SIP). This disposable module comes pre-assembled with a tubing set and can be connected to the user's bioreactor via thermal welding (customized connectors are available upon request).The entire process is fully automated, with flexible cycle parameter settings. The cell culture feed is pumped into the single-use module, where centrifugal force sediments the cells against the outer wall, while the clarified supernatant is continuously discharged. Once a user-defined cycle is complete, the controller stops the rotor and discharges the concentrated cells. This process can be repeated automatically for a preset number of cycles, based on the bioreactor volume. The centrifuge is equipped with a cooling system that maintains an operating temperature of 3–8°C, thereby enhancing cell viability.2. Product SpecificationsTechnical SpecificationsOperating Environment: Ambient Room TemperatureDimensions (W × D × H): 73 cm × 58 cm × 93 cmWeight: Approximately 60 kgDisplay: 10-inch Touchscreen InterfaceConnectionsTubing access port located on the front-left sideElectrical and gas source interfaces located on the right sideCooling System: Maintains the single-use centrifugal module temperature at 3–8°CUnit Supply RequirementsClean Dry Air: 1 bar, 10 liters/minPower Supply: 220 V / 50 Hz, 4 AConfiguration: Four (4) Pinch ValvesFeed ValveConcentrate ValveSupernatant ValveBuffer ValveSingle-Use Centrifugal ModuleFluid Operating Temperature Range: 4 – 38°C (39 – 100°F)Module Capacity: 275 mLTubing Material: SiliconeProcess Flow: Continuous Supernatant Discharge & Intermittent Cell DischargeSterilization: Gamma IrradiatedContact UsEmail:jiangying@sh-biochem.comWebsite:www.bio-eq.comPhone:+86 136 8168 7967Company:Shanghai Biochem Biotech Co., Ltd.
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