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Continuous Flow Cell Concentrator

Continuous Flow Cell ConcentratorThe Ideal Choice for Personalized MedicineShanghai Biochem Biotech Co., Ltd.1. Product OverviewDesigned for harvesting CHO cells, stem cells, and other cell types, this system is widely used in the biotechnology and pharmaceutical industries. It is capable of collecting stem cells, CHO cells, immune cells, and other particles for biotech and pharmaceutical applications. Suitable for a broad range of users in cell therapy, antibody production, vaccine development, gene therapy, and mRNA research, including major pharmaceutical companies and biotech research institutions. User-friendly by design, it can be operated on a laboratory benchtop, within a cleanroom, or under a laminar flow hood.System FeaturesFully Closed SystemNo CIP or SIP RequiredHigh Cell Recovery RateLightweight Single-Use Module with Tubing AssemblyMaximum Relative Centrifugal Force of 6,600 × gContinuous Clarified Liquid Discharge & Intermittent Cell DischargeLow-Shear Separation ProcessRapid Single-Use Module Change-Out in Under 15 MinutesIntegrated Cooling System for High Cell Viability Post-HarvestFlow Rate Range: 10 to 1,200 mL/minThe separation system utilizes a gamma-irradiated, sterile single-use centrifugal module, eliminating the need for Clean-in-Place (CIP) or Sterilize-in-Place (SIP). This disposable module comes pre-assembled with a tubing set and can be connected to the user's bioreactor via thermal welding (customized connectors are available upon request).The entire process is fully automated, with flexible cycle parameter settings. The cell culture feed is pumped into the single-use module, where centrifugal force sediments the cells against the outer wall, while the clarified supernatant is continuously discharged. Once a user-defined cycle is complete, the controller stops the rotor and discharges the concentrated cells. This process can be repeated automatically for a preset number of cycles, based on the bioreactor volume. The centrifuge is equipped with a cooling system that maintains an operating temperature of 3–8°C, thereby enhancing cell viability.2. Product SpecificationsTechnical SpecificationsOperating Environment: Ambient Room TemperatureDimensions (W × D × H): 73 cm × 58 cm × 93 cmWeight: Approximately 60 kgDisplay: 10-inch Touchscreen InterfaceConnectionsTubing access port located on the front-left sideElectrical and gas source interfaces located on the right sideCooling System: Maintains the single-use centrifugal module temperature at 3–8°CUnit Supply RequirementsClean Dry Air: 1 bar, 10 liters/minPower Supply: 220 V / 50 Hz, 4 AConfiguration: Four (4) Pinch ValvesFeed ValveConcentrate ValveSupernatant ValveBuffer ValveSingle-Use Centrifugal ModuleFluid Operating Temperature Range: 4 – 38°C (39 – 100°F)Module Capacity: 275 mLTubing Material: SiliconeProcess Flow: Continuous Supernatant Discharge & Intermittent Cell DischargeSterilization: Gamma IrradiatedContact UsEmail:jiangying@sh-biochem.comWebsite:www.bio-eq.comPhone:+86 136 8168 7967Company:Shanghai Biochem Biotech Co., Ltd.
  • Commodity name: Continuous Flow Cell Concentrator

Details

  • 产品描述
  • Continuous Flow Cell Concentrator

    The Ideal Choice for Personalized Medicine

    Shanghai Biochem Biotech Co., Ltd.

    1. Product Overview

    Designed for harvesting CHO cells, stem cells, and other cell types, this system is widely used in the biotechnology and pharmaceutical industries. It is capable of collecting stem cells, CHO cells, immune cells, and other particles for biotech and pharmaceutical applications. Suitable for a broad range of users in cell therapy, antibody production, vaccine development, gene therapy, and mRNA research, including major pharmaceutical companies and biotech research institutions. User-friendly by design, it can be operated on a laboratory benchtop, within a cleanroom, or under a laminar flow hood.

    System Features

    • Fully Closed System
    • No CIP or SIP Required
    • High Cell Recovery Rate
    • Lightweight Single-Use Module with Tubing Assembly
    • Maximum Relative Centrifugal Force of 6,600 × g
    • Continuous Clarified Liquid Discharge & Intermittent Cell Discharge
    • Low-Shear Separation Process
    • Rapid Single-Use Module Change-Out in Under 15 Minutes
    • Integrated Cooling System for High Cell Viability Post-Harvest
    • Flow Rate Range: 10 to 1,200 mL/min

    The separation system utilizes a gamma-irradiated, sterile single-use centrifugal module, eliminating the need for Clean-in-Place (CIP) or Sterilize-in-Place (SIP). This disposable module comes pre-assembled with a tubing set and can be connected to the user's bioreactor via thermal welding (customized connectors are available upon request).

    The entire process is fully automated, with flexible cycle parameter settings. The cell culture feed is pumped into the single-use module, where centrifugal force sediments the cells against the outer wall, while the clarified supernatant is continuously discharged. Once a user-defined cycle is complete, the controller stops the rotor and discharges the concentrated cells. This process can be repeated automatically for a preset number of cycles, based on the bioreactor volume. The centrifuge is equipped with a cooling system that maintains an operating temperature of 3–8°C, thereby enhancing cell viability.

    2. Product Specifications

    Technical Specifications

    Operating Environment: Ambient Room Temperature

    Dimensions (W × D × H): 73 cm × 58 cm × 93 cm

    Weight: Approximately 60 kg

    Display: 10-inch Touchscreen Interface

    Connections

    • Tubing access port located on the front-left side
    • Electrical and gas source interfaces located on the right side

    Cooling System: Maintains the single-use centrifugal module temperature at 3–8°C

    Unit Supply Requirements

    • Clean Dry Air: 1 bar, 10 liters/min
    • Power Supply: 220 V / 50 Hz, 4 A
    • Configuration: Four (4) Pinch Valves
    • Feed Valve
    • Concentrate Valve
    • Supernatant Valve
    • Buffer Valve

    Single-Use Centrifugal Module

    • Fluid Operating Temperature Range: 4 – 38°C (39 – 100°F)
    • Module Capacity: 275 mL
    • Tubing Material: Silicone
    • Process Flow: Continuous Supernatant Discharge & Intermittent Cell Discharge
    • Sterilization: Gamma Irradiated

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