Your Lab Expert 4.6


离心机性能评测与对比验证系列

Centrifuge Performance Evaluation Series

性能比肩进口,国产替代正当时

On Par with Imports, Domestic Substitution Is Now

【总结篇/ Conclusion

一、回顾  Series Recap

Episode

Topic

Headline

No.1

离心力调节

30g — 3479g1g 步进

No.2

温度控制

±2℃ 以内,10 min 重复一致

No.3

PBMC 分离

得率与活率与Eppendorf 5810R 等价

No.4

流式表型

个 marker54 个数据点全部一致

No.5

综合结论

可作为实验室主用或备用离心机

二、综合评分  Composite Score

Dimension

T520R

Eppendorf 5810R

差距/ Gap

离心力范围

Force Range

30g — 3479g

100g — 3500g

T520R 略优

调节步进

Step

1g

50g — 100g

T520R 明显优

温控稳定

Temp. Control

±2

±3

T520R 略优

PBMC 活率 

Viability

95.6% — 97.25%

95.45% — 97.1%

等价

PBMC 得率 

Recovery

76.1% — 80.6%

73.5% — 81.6%

等价

流式一致性

Phenotype

9/9 marker 一致

9/9 marker 一致

等价

采购成本

Capex

国产/ Domestic

进口/ Imported

T520R 

使用经济性

Service Life

— 10 

等价

三、原文结论  Verbatim Conclusion from the Report

1.与 Eppendorf 离心机相比,T520R 离心机离心力调节范围更广,且单次调节幅度更加精细。离心机腔体温度稳定性较高,可控制在 ±2℃ 之间。

Compared with the Eppendorf centrifuge, the T520R offers a wider RCF adjustment range with finer step size. Chamber temperature stability is high, controllable within±2.

2.综合密度梯度离心分离PBMC 和高离心力去除血小板的角度评价,T520R 离心机与目前实验室常用离心机(Eppendorf)表现近似,可以作为实验室常用离心机的备用选择。

Evaluating density-gradient PBMC separation and high-RCF platelet removal comprehensively, the T520R performs comparably to the lab-standard Eppendorf, and can serve as a backup centrifuge for routine lab use.

四、决策建议  Recommendations

1.适合立即采购的实验室类型  

Labs That Should Consider It Now

● 细胞治疗与免疫学研究中心(CAR-T / TIL / 移植免疫)  

Cell therapy & immunology research centers (CAR-T / TIL / transplant immunology)

● 大规模PBMC 库、单细胞测序中心  

Large-scale PBMC banks, single-cell sequencing centers

● 新建/扩建中的第三方检测实验室  

New/expanding third-party testing laboratories

● 需要+双机配置以应对 GMP 审计的生物药企  

Biopharma companies needing "primary + backup" configuration for GMP audit compliance

2.推荐采购与验证路径  

Recommended Procurement Path

Step 1. 实验室自测1周(PBMC + 蛋白沉降 + RNA 提取)  

Lab self-test 12 weeks (PBMC + protein precipitation + RNA extraction)

Step 2. 跨中心盲样对比(建议家独立实验室)  

Cross-center blind comparison (3 independent labs recommended)

Step 3. SOP 转移与 IQ/OQ 验证(可委托 T520R 工程团队支持)  

SOP transfer and IQ/OQ validation (T520R engineering team can support)

Step 4. 纳入年度校准计划,承接主用或备机角色  

Incorporate into annual calibration plan, assume primary or backup role

3.性价比测算参考  

TCO Illustration

● 进口台式冷冻离心机:整机采购约¥20万 + 5 年维保 ¥2  

Imported benchtop refrigerated centrifuge: ~¥200K + 5yr service¥20K

● T520R:整机采购约 ¥5.5万 + 5 年维保 ¥0.5  

T520R: ~¥55K + 5yr service¥5K

● 在等同性能下,年 TCO 节省估算约200%300%(具体以询价为准)  

At equivalent performance, 5-year TCO savings estimated at200%300% (subject to quotation)

五、致谢与声明  Acknowledgement & Disclaimer

数据透明,欢迎复核

本系列全部数据来自合佑生生物内部对照实验的原始报告,原始PDF 与 DOCX 可向合佑生技术团队申请查阅。

All data in this series comes froShanghai Hyogen's internal controlled experiments. Original PDF and DOCX reports are available upon request from the Hyogen technical team.

数据不说谎,性能比肩进口,国产替代正当时。

Data tells the truthdomestic centrifuges are ready, and the timing is now.

End



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